Comparison · Prostate Biopsy
Transperineal vs transrectal biopsy is a route decision, not a fear decision.
Both biopsy routes can diagnose prostate cancer. The choice depends on infection-risk history, lesion location, anesthesia, practice protocol, and physician judgment.
What patients should ask
Ask why one route is being recommended, whether MRI-targeted samples will be taken, and what infection and urinary-retention precautions apply.
After biopsy
Pathology drives next steps, but PSA or MRI concern may still require follow-up even after a negative biopsy.